- October 07, 2010
October 7, 2010 - FOSS NIRSystems offers a 12 mm BioProcess Probe optimized for real-time in-situ monitoring of mammalian cell culture growth media in bioreactors. With a variable pathlength that can be optimized for culture media, this design is autoclavable or sterilizable-in-place (SIP). The small diameter probe is designed for use in standard instrument ports in benchtop bioreactors and can be adapted for scale up to pilot plant and manufacturing reactors. Real-time analysis of nutrients and metabolites will lead to optimized cell culture performance, increased cell viability and bioprocess understanding.Up to nine bioprocess probes can be multiplexed to one FOSS XDS Process Analytics Near-Infrared (NIR) Analyzer. Our rugged analyzers track key low concentration analytes in the culture growth media, enabling optimization of the fermentation. Feedback control is available through OPC or digital protocols.