SHREWSBURY, MA, Dec. 9, 2025 – PI (Physik Instrumente), a global leader in nanopositioning and precision motion systems, has announced the launch of its newest 6-axis piezo alignment platform: the P-616.65S NanoCube 6-DOF piezo-flexure nanopositioning system. With 500µm linear travel in X, Y and Z, a rotational range of 3° in θX, θY, θZ and true parallel-kinematic 6-DOF motion, the new platform establishes a new standard for compactness, dynamic performance and precision in photonics, semiconductor and microscopy applications. A user programmable virtual pivot point (center of rotation) and high-speed alignment routines built directly into the digital controller firmware further enhance versatility, accelerating setup and throughput.
High stiffness = High dynamics and rapid step and settle
Its integrated, rigid and friction-free flexure structure provides high stiffness—characterized by a resonant frequency of 350 Hz—and enables fast dynamics with rapid step-and-settle performance, ideal for fast scanning and automated multi-channel photonics alignment.
Powered by PICMA all-ceramic actuators with demonstrated 100-billion-cycle lifetime, the system offers exceptional reliability even in 24/7 high-duty-cycle environments. Closed-loop position control with high-resolution sensors delivers nanometer-level repeatability across all motion axes.
Key technical highlights:
- Ultra-compact 6-axis alignment system—small enough to fit in the palm of your hand
- 500µm travel range in X, Y and Z
- 3° rotation in θX, θY, θZ for full 6-DOF adjustment
- User-selectable virtual pivot point—in software for intuitive multi-axis alignment
- Nanometer level resolution and repeatability for reduced insertion loss
- Parallel-kinematic flexure design for uniform stiffness and zero friction
- Compact aluminum construction, vacuum-compatible and resistant to shock and vibration
Smart firmware for faster alignment
In combination with PI’s E-713 digital nanopositioning controllers the new NanoCube aligner features embedded high-speed routines for first-light detection, gradient search, coordinate scans and multi-axis optimization. By eliminating the need for external scripts or PC-side computation, these firmware algorithms significantly shorten alignment times in production workflows.
A compact workhorse for advanced photonics
The NanoCube complements a wide range of advanced and proven alignment solutions that PI offers to the photonics industry—from its award-winning hexapod-based FMPA system to its cost- and throughput-optimized modular PINovAlign product family. As manufacturers continue to push for smaller footprints and higher throughput, this new piezo-flexure-based solution provides a powerful tool for high-volume photonics assembly and testing.
The new NanoCube automated alignment system is available now for OEM integration, research laboratories and fully automated photonics-alignment subsystems.


